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Wednesday, June 15, 2011
Genetically Engineered Cell Shoots Out First-Ever Biological Laser
Some cells fight disease. Other cells form hair and bone. And now, thanks to some fancy genetic engineering and a pair of tiny mirrors, a specially altered kidneycells shoot the first-ever biological laser beams. By harnessing the light-emitting power of green florescent protein (GFP), scientists working at Massachusetts General Hospital created the biological laser merely as a proof of concept. Aside from implying the future possibility of a self-healing laser that requires no battery, this breakthrough could allow doctors and scientists to view the inner workings of individual cells without a microscope. GFP protein acts as a copy machine of sorts, absorbing regular blue light and releasing identical particles of green light. Whereas regular light contains light particles in a range of different wavelength frequencies, laser beams contain only coherent light particles with the same profile. Since GFP always releases light particles with the same profile, the scientists simply needed to funnel the light into a single beam to create the biological laser.
As expected, the laser emitted by Gather′s cells lacks the power of commercial lasers, limiting immediate practical uses. However, since the internal components of the cell shapes the laser beam, this technology could provide researchers with a tool for producing detailed images of microorganisms without using a microscope. "One neat application of a living laser beam is that, GFP, like most laser materials, degrades over time. But the fact that the cell is alive means that the laser can self-heal," Gather said. "Lasers have the notorious quality of just dying sometimes. If the GFP gets degradeds, the cells can just make more of it. Very long term, this could be an interesting advantage to having a living cell producing laser light." Technews Daily
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