NEW YORK – Scientists are reporting early success at transforming one kind of specialized cell into another, a feat of biological alchemy that doctors may someday perform inside a patient's body to restore health. So if a heart attack damages muscle tissue in the heart, for example, doctors may someday be able to get other cells in that organ to become muscle to help the heart pump.
That's a futuristic idea, but researchers are enthusiastic about the potential for the new direct-conversion approach.
"I think everyone believes this is really the future of so-called stem-cell biology," says John Gearhart of the University of Pennsylvania, one of many researchers pursuing this approach.
The concept is two steps beyond the familiar story of embryonic stem cells, versatile entities that can be coaxed to become cells of all types, like brain and blood. Scientists are learning to guide those transformations, which someday may provide transplant tissue for treating diseases like Parkinson's or diabetes. AP
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